Glycyrrhizic Acid: A Natural Plant Ingredient as a Drug Candidate to Treat COVID-19
نویسندگان
چکیده
The total number of cumulative cases and deaths from the COVID-19 pandemic caused by SARS-CoV-2 is still increasing worldwide. Although many countries have actively implemented vaccination strategies to curb epidemic, there no specific efficient therapeutic drug for this virus effectively reduce deaths. Therefore, underappreciated macromolecular compounds become spotlight research. Furthermore, medicinal in plants that provide myriad possibilities treat human diseases utmost importance. Experience indicates Traditional Chinese medicine treats SARS has been used treating patients with China. As one world’s oldest herbal remedies, licorice all stages COVID-19. Glycyrrhizic acid (GA), main active compound licorice, proven effective killing virus. Meanwhile, as a natural plant molecule, GA can also directly target important protein structures inhibit replication SARS-CoV-2. In review, we summarized immune synergy its potential role complications. Besides, reviewed anti-inflammatory effects on system positive cooperation various drugs fight against comorbidities. purpose review elucidate suggest be during treatment.
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2021
ISSN: ['1663-9812']
DOI: https://doi.org/10.3389/fphar.2021.707205